"I went to ChatGPT and came up with a plan on how to do this. He also used AlphaFold, an AI tool from Google's DeepMind, to find mutated proteins that could be potential targets for treatment. While an immunotherapy treatment that looked like a good fit for Rosie was identified, the drugmaker wouldn't provide it."
"This is the first time a personalized cancer vaccine has been designed for a dog. This is still at the frontier of where cancer immunotherapeutics are-and ultimately, we're going to use this for helping humans. What Rosie is teaching us is that personalized medicine can be very effective, and done in a time-sensitive manner, with mRNA technology."
Paul Conyngham, a tech entrepreneur and electrical engineer, turned to artificial intelligence when his dog Rosie's cancer persisted despite chemotherapy and surgery. Using ChatGPT for guidance, he connected with researchers at the University of New South Wales and obtained Rosie's genomic sequencing. Conyngham employed AlphaFold, Google DeepMind's AI tool, to identify mutated proteins as treatment targets. When conventional immunotherapy proved unavailable, nanomedicine pioneer Pall Thordarson developed a custom mRNA vaccine in under two months. After receiving injections in December and February, most of Rosie's tumors shrank significantly, and the dog recovered her normal activity levels. This represents the first personalized cancer vaccine designed for a dog and demonstrates mRNA technology's potential for time-sensitive, personalized medicine.
Read at Fortune
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