""So far in 2026, California is experiencing more than double the average weekly number of clade II cases compared to the same period in previous years - 14.5 weekly cases in 2026 compared to 5.8 in 2024 and 3.4 in 2025.""
""CDPH is closely monitoring mpox activity across California. While Clade I cases remain uncommon, Clade II mpox continues to circulate and we're seeing rising cases.""
""This reinforces how important it is for people at higher risk to get both doses of the mpox vaccine. With summer travel and large events approaching, now is the ideal time to protect yourself if you or your sex partner may be at risk.""
California health officials are urging at-risk individuals to receive the mpox vaccine due to rising cases. Clade I mpox cases have been identified, with the first in San Francisco in April 2026. Clade II cases are increasing, with 14.5 weekly cases reported in 2026, more than double the average from previous years. The vaccine, administered in two doses, protects against both clades. The CDPH is monitoring the situation closely, emphasizing the importance of vaccination for those at higher risk, especially with summer events approaching.
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