"Uri Alon noted that earlier studies estimating lifespan heritability were based on Scandinavian twins from the late 19th century, a time when extrinsic mortality was high due to factors like infections and accidents. This high extrinsic mortality masked the true genetic contribution to lifespan."
"The new study found that when extrinsic deaths were accounted for, the heritability of lifespan increased to about 50%. Alon emphasized that the old studies were not wrong but were limited by the context of their time, where many individuals did not survive past their 40s."
Research indicates that genetic factors contribute to approximately 50% of human lifespan, a significant increase from the previously believed 20%. This conclusion arises from a study that reexamined data on Swedish twins born between 1900 and 1935, revealing that earlier estimates were skewed by high extrinsic mortality rates. By applying a mathematical model to filter out these extrinsic deaths, the inherited component of lifespan was clarified, demonstrating that the environment and lifestyle factors also play a crucial role in longevity.
Read at The Washington Post
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