"Mitochondria control much more than energy production. They regulate calcium, initiate cell death (apoptosis), and produce reactive oxygen species (ROS). When ROS accumulate, they produce oxidative stress."
"Chronic stress damages mitochondria, impairing neuroplasticity and driving treatment-resistant depression. Mental illness can be understood, at least in part, as a disease of the mitochondria."
Mitochondrial dysfunction significantly contributes to mental health disorders such as depression, bipolar disorder, and schizophrenia. Chronic stress damages mitochondria, impairing neuroplasticity and leading to treatment-resistant depression. Mitochondria, often referred to as the powerhouse of the cell, play a crucial role beyond energy production, including regulating calcium and initiating cell death. The brain, which consumes a large portion of the body's energy, relies heavily on mitochondrial efficiency. Oxidative stress from accumulated reactive oxygen species further destabilizes mitochondrial function, impacting emotional regulation and cognitive processes.
Read at Psychology Today
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