Kitty Flipping: Ketamine and MDMA Stimulant Combinations
Briefly

Kitty Flipping: Ketamine and MDMA Stimulant Combinations
"Kitty flipping, the practice of combining MDMA (ecstasy) and ketamine, is often confused with the term "candy flipping," in which MDMA is combined with LSD. Historically, kitty flipping refers to the use of MDMA and ketamine within the same short time period, but new drug seizure data suggest that MDMA and ketamine are also pre-mixed and sold for "kitty flipping"."
"Dr. Moore said the 2025 deaths in Miami so far follow a national increase of ketamine-associated deaths. Until 2017, ketamine was identified in fewer than 10 deaths yearly. But in the first half of 2025 in Miami-Dade County, coroners reported 33 fatal toxicology reports implicating ketamine-a sharp rise highlighting an alarming trend. Illicit forms of ketamine are most often mixed with MDMA."
Kitty flipping refers to combining MDMA and ketamine, distinct from candy flipping which pairs MDMA with LSD. Recent drug seizure data indicate MDMA and ketamine are sometimes pre-mixed and sold for kitty flipping. Miami-Dade toxicology data show a sharp rise in ketamine-implicated deaths in 2025, following a national increase; coroners reported 33 fatal toxicology reports implicating ketamine in the first half of 2025. Ketamine has been common in clubs and festivals since the 1980s, often used concurrently with stimulants, and surveys and early warning systems documented rising ketamine use through the early 2020s.
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