"Two milligrams of fentanyl can be deadly: The U.S. Drug Enforcement Administration says that ingesting as little as 2 milligrams of fentanyl can be deadly for an adult. The drug is similar to morphine, but up to 100 times more potent, which is what makes it so lethal. Different people can tolerate different doses, but it's hard to know how much is in a pill:"
"Fentanyl overdose deaths have recently dropped. From April 2024 to March 2025, the CDC reported 43,000 synthetic opioid deaths, most of which are from fentanyl, down from nearly 70,000 in the previous similar period. You probably already know this part: Even tiny amounts of fentanyl can be lethal. But we've come across a fair number of myths about fentanyl over the years. Knowing the facts about this potent drug can help save lives."
Federal agencies and advocacy groups mark an awareness day to signal the seriousness of fentanyl's toll. Fentanyl, a synthetic opioid up to 100 times more potent than morphine, has driven soaring U.S. opioid overdose deaths over the past decade. Reported synthetic opioid deaths fell from nearly 70,000 to 43,000 between comparable recent 12‑month periods. Ingesting as little as two milligrams can be lethal for an adult. Individual tolerance varies by height, weight and opioid history, and pill dosages can vary widely. Fentanyl is often used to cut heroin, cocaine and methamphetamines, leading to unintentional exposure. Accurate facts and awareness can prevent deaths.
Read at Poynter
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