"Shanahan's teams are 7-9 against the Cardinals against four different coaches Bruce Arians, Steve Wilks, Kliff Kingsbury and Jonathan Gannon. When you change coaches it's always different with scheme and stuff, Shanahan said Wednesday. And when you've got a quarterback like Kyler (Murray), regardless of who the game's going or how good you're doing you never know when he can do something off schedule. There's not anything in particular, they've got good coaches and good players."
"A look at those 16 games: Jan. 5, 2025 CARDINALS 47, 49ers 24: Arizona outscores the 49ers 19-0 in the fourth quarter. Josh Dobbs passes for 326 yards but is intercepted twice. Kyler Murray is 25-foir-35 for 242 yards, 4 TDs Oct. 6, 2024 Cardinals 24, 49ERS 23: Shanahan was 38-0 with a 10-point lead in the fourth quarter. Murray opened the scoring with a 50-yard run but 49ers led 23-10 before letting it get away. Brock Purdy had two interceptions."
Kyle Shanahan is in his ninth NFL season and his teams are 7-9 versus the Arizona Cardinals across four different Cardinals coaches: Bruce Arians, Steve Wilks, Kliff Kingsbury and Jonathan Gannon. The 49ers were swept last season, including a 24-23 loss at Levi's Stadium after leading 23-10 entering the fourth quarter. Shanahan emphasized that coaching changes alter scheme and noted Kyler Murray's ability to create off-schedule plays. Recent notable games include a 47-24 Cardinals win on Jan. 5, 2025, a 24-23 Cardinals win on Oct. 6, 2024, and dominant 49ers victories in 2023 featuring Christian McCaffrey.
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