Lithium supplements have shown potential in reversing Alzheimer's disease-related brain changes in mice, suggesting a novel treatment pathway. Additionally, researchers have identified at least 30 parent-of-origin effects among 14 genes, revealing that the inheritance pattern can drastically change a gene's effect. For instance, one gene variant raises the risk of type 2 diabetes by 14% if inherited from the father, while inheritance from the mother reduces the risk by 9%. Furthermore, the UK Royal Society will shift to a 'subscribe to open' model for eight of its ten journals, allowing free access content based on library participation.
Researchers have found that supplements containing lithium reverse brain changes associated with Alzheimer's disease in mice, presenting a potential avenue for treatment.
At least 30 parent-of-origin effects across 14 genes were identified, showing how inheritance from mother or father can drastically alter gene expression and associated risks.
A variant that increased type 2 diabetes risk by 14% when inherited from the father had the opposite effect, decreasing risk by 9% when inherited from the mother.
The UK Royal Society plans to transition eight of its ten journals to a 'subscribe to open' model, which will provide open access content free under certain conditions.
#alzheimers-disease #gene-variants #parent-of-origin-effects #open-access-publishing #artificial-intelligence
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