Litestar is worth a look
Briefly

Litestar is an async-first, type-hint-driven Python web framework that distinguishes itself within the ecosystem. Even those experienced with Python web apps may not be familiar with its features. A simple application can be set up using a single file where required parameters are easily handled. The framework compares favorably against others like FastAPI and traditional Java or .NET frameworks, reminding users of the effective parts of those systems. Litestar remains a compelling choice due to its simplicity and practical deployment capabilities in building web applications.
Litestar stands out in the Python web ecosystem as a unique async-first, type-hint-driven framework, attracting positive attention due to its simplicity and ease of use.
With a traditional single-file demo, Litestar allows rapid deployment of web applications, supporting essential features like required parameters and straightforward routing.
Read at James Bennett
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