#broadly-neutralizing-antibodies

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fromNature
3 days ago

Vaccination generates broadly cross-neutralizing antibodies to the HIV Env apex - Nature

The sole neutralizing determinant on the surface of the virus is the trimeric envelope glycoprotein (Env) spike, which has evolved to evade host antibody responses by incorporating host-derived N-glycans and altering variable domains during replication.
Medicine
Medicine
fromNational Institute of Mental Health (NIMH)
1 month ago

Immunotherapies for HIV Eradication in the CNS Compartment

Immunotherapeutic strategies using broadly neutralizing antibodies must overcome blood-brain barrier limitations to effectively target persistent HIV in the central nervous system while preventing neuroinflammatory damage.
#hiv
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