#targeted-therapy

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#brd4 #transcription-regulation #bet-proteins #bet-family #antibody-drug-conjugates #breast-cancer
Science
fromNews Center
6 days ago

New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve Targeted Therapies - News Center

BET proteins, particularly BRD4, regulate transcription initiation and elongation independently of bromodomains, with implications for targeted therapeutic development.
Science
fromNews Center
6 days ago

New Underlying Mechanisms May Support Proper Transcriptional Regulation and Improve - News Center

New mechanisms controlling transcription initiation and elongation involving BET family proteins were identified, revealing pathways that could enable improved targeted therapies for diseases including cancer.
Medicine
fromenglish.elpais.com
3 months ago

Guided missiles targeting tumor cells open a new route to combat cancer

Antibody-drug conjugates (ADCs) deliver chemotherapy directly into tumor cells, showing promising efficacy across multiple cancers including breast, ovarian, endometrial, and pancreatic tumors.
Cancer
fromwww.theguardian.com
7 months ago

UK-wide drug trial hailed as a milestone' in leukaemia treatment

A UK trial found a chemotherapy-free treatment for leukaemia that improves outcomes for patients, suggesting a significant shift in treatment approaches.
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