"Endometriosis is still widely misunderstood and under-diagnosed, with many people waiting years for answers. Through our research, we're trying to better understand not only how the disease develops, but how it may interact with other serious conditions such as ovarian cancer."
"We're looking at whether chemical signals from endometriosis cells can essentially 'support' cancer cells. For example, by helping them hide from the immune system. If we can prove that link, it opens the door to new ways of targeting those interac"
"Research suggests people with endometriosis are between two and four times more likely to develop ovarian cancer, although the overall risk remains low. One sub-type, ovarian clear cell carcinoma, has a particularly strong connection to the condition."
"Scientists are using laboratory-grown cell models and three-dimensional bioprinting technology to recreate the early stages of disease development. The aim is to examine whether signals from endometriosis cells could encourage cancer cells to grow, spread or evade immune responses."
Researchers at the University of Northampton are studying whether endometriosis influences the development of ovarian cancer. The work led by Danielle Jex examines whether chemical signals released by endometriosis cells can affect the growth and spread of specific ovarian cancer types. The project investigates whether these signals help cancer cells survive and avoid immune system detection. Endometriosis affects one in 10 women in the UK and often involves extremely heavy periods, debilitating pain, and sometimes infertility, with an average diagnosis delay of nine years and four months. Evidence suggests people with endometriosis have a higher likelihood of developing ovarian cancer, especially ovarian clear cell carcinoma. Laboratory-grown cell models and three-dimensional bioprinting recreate early disease stages to test how endometriosis signals may support cancer progression and immune evasion.
Read at www.bbc.com
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