
"“The original name derived from a common feature of the condition polycystic ovaries. But the moniker is misleading. It implies there are cysts in the ovaries, Duncan says. But that's not the case.”"
"“He says the erroneous name probably arose when researchers first looked at the ovaries of people with the condition and saw multiple small fluid-filled sacs. These sacs are not cysts, they are follicles structures that contain an egg.”"
"“In healthy women, multiple follicles start to develop within an ovary each month, a process that eventually leads to one reaching maturity and releasing an egg, while the others wither away. In women with PMOS the development of some follicles becomes paused, and often a follicle does not mature to release an egg.”"
"“The development of polycystic ovaries is associated with another common hallmark of the condition: an overproduction of androgens by the ovaries. These male sex hormones are produced in all women but people with PMOS often have an excess. This overproduction is usually caused by an imbalance between two other hormones: follicle-stimulating hormone and luteinising hormone.”"
PMOS is a multifaceted condition with symptoms that often begin in late adolescence. Common features include irregular or absent periods, irregular ovulation, extra facial or body hair, acne, weight gain, and hair loss from the head. Presentation can vary across different life stages. The older name PCOS is considered misleading because the “cysts” are not cysts; they are follicles containing eggs. In healthy ovaries, multiple follicles develop each month, one matures and releases an egg, and others regress. In PMOS, follicle development can pause and follicles may not mature to release an egg. Overproduction of androgens is another hallmark, linked to an imbalance between follicle-stimulating hormone and luteinising hormone, with insulin resistance often worsening androgen excess.
Read at www.theguardian.com
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