"The plan is to create an inter-breedable population of dire wolves in which they would eventually breed naturally to create a sustainable population of the world's first de-extinct species. We will grow the population through assisted reproduction initially and then eventually only rely on natural breeding."
"To create the dire wolves, Colossal Biosciences started by reconstructing their genome from DNA found in ancient fragments of bone. Using this genome as a reference, scientists then genetically modified grey wolf embryos so that they closely resembled the extinct dire wolf. This meant inserting traits for a white coat, larger teeth, a more muscular build and a distinctive howl."
"The three dire wolves live on a 2,000-acre secure, expansive ecological preserve that allows us to monitor and care for them while they continue to develop and reach breeding maturity, representing a major milestone in de-extinction technology and species restoration efforts."
Colossal Biosciences announced the successful de-extinction of dire wolves, a species extinct for 12,000 years. The first litter produced two male pups, Romulus and Remus, followed by a female named Khaleesi. These apex predators are thriving at a secure US preserve and have reached developmental milestones including learning to process whole deer carcasses. The pups are now ready to breed. The company plans to create additional pups to expand the gene pool and establish a sustainable population. Scientists reconstructed the dire wolf genome from ancient bone DNA, then genetically modified grey wolf embryos to include dire wolf traits such as white coats, larger teeth, muscular builds, and distinctive howls. Hybrid embryos were implanted in surrogate dog mothers via caesarean section.
Read at Mail Online
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