"There hasn't been prior work that shows if timely pain relief can impact important patient-centered outcomes like admission to the hospital."
"If we can stabilize and treat patients' pain, they won't need to be admitted to the hospital, where they would miss school, their families would miss work, and it's disruptive to their lives."
"We were able to statistically show that if patients receive a timely first dose of opioid medications and a timely second dose of opioid medications, we could drastically reduce the number of hospital admissions within this population,"
Prompt opioid administration in emergency departments substantially reduces hospital admissions among children with sickle cell disease. Sickle cell disease causes severe, intense pain episodes due to blocked blood flow. National guidelines recommend prompt opioid treatment for acute SCD pain. Data from the Pediatric Emergency Care Applied Research Network Registry included over 9,000 emergency visits by 2,538 children under 19 from 2019–2021. Faster provision of both first and second opioid doses correlated with markedly lower admission rates. Reducing admissions prevents missed school, decreases caregiver work loss, and reduces disruption to family life.
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