Recent research identified a brain signal in mice that triggers the overwriting of fearful memories after perceived danger has passed, known as fear extinction. This early-stage study, published in the Proceedings of the National Academy of Sciences, focuses on two types of neurons in the basolateral amygdala. One type stimulates fear responses, while the other suppresses them. The findings may contribute to drug development for psychological conditions like PTSD, stemming from distressing memories, enhancing our understanding of fear management mechanisms in the brain.
The research shows that a certain brain signal in mice can facilitate the overwriting of fearful memories, paving the way for potential PTSD treatments.
Co-author Michele Pignatelli highlights the contrasting effects of two types of neurons in the basolateral amygdala, crucial for managing fear response.
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