Medicine
fromPsychology Today
3 days agoADHD Meds Might Not Work the Way We Thought, New Study Finds
Stimulant medications do not activate attention networks in the prefrontal cortex but alter connectivity in arousal and reward centers.
Neuroscientists have a name for the brain network that fires up when you're not focused on an external task: the default mode network, or DMN. It's the constellation of regions - the medial prefrontal cortex, posterior cingulate cortex, and angular gyrus among them - that hums to life when you daydream, reflect on yourself, or think about other people's mental states.
Researchers studying brain-imaging data from people aged between 8 and 100 found that sex differences in the brain's connections are minimal in early life, but then increase drastically at puberty; some of these differences continue to grow throughout adult life. The study was published as a preprint on bioRxiv, and has not yet been peer reviewed. The work could help us to understand why men and women have different likelihoods of developing some mental-health disorders - and perhaps give insight into treating them, say the researchers.
They then used emerging mathematical methods to isolate signals originating from nine brain regions previously implicated in mediating consciousness and examined connections between pairs of these regions. Among them were the parietal cortex, which is at the top of the brain about halfway between the forehead and the back of the skull; the occipital cortex, at the back of the head; and several small, deeper structures, such as one called the thalamus.