#clinical-trials

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#psychedelic-therapy
fromNews Center
1 week ago

'Dancing Molecules' Treatment Receives FDA Orphan Drug Designation - News Center

"Dancing molecules," the promising new treatment for acute spinal cord injuries developed at Northwestern University, has received Orphan Drug Designation from the U.S. Food and Drug Administration (FDA).
Science
#drug-development
Tech industry
fromHackernoon
5 months ago

Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoon

Quantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
Tech industry
fromHackernoon
5 months ago

Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoon

Quantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
fromwww.scientificamerican.com
1 week ago

Male Birth Control Pill to Stop Sperm Production Passes Safety Test

YCT-529 is a hormone-free pill that blocks a vitamin A metabolite to stop sperm production, deemed safe for human use in trials.
#parkinsons-disease
fromNature
3 months ago
Alternative medicine

Daily briefing: The biggest single piece of meat ever grown in the lab

Alternative medicine
fromNature
3 months ago

'Big leap' for Parkinson's treatment: symptoms improve in stem-cells trials

Early-stage stem cell trials show promise for treating Parkinson's disease by replacing lost dopamine-producing neurons.
Wearables
fromwww.scientificamerican.com
4 months ago

New Form of Parkinson's Treatment Uses Real-Time Deep-Brain Stimulation

Deep-brain stimulation technology has dramatically improved symptoms for Parkinson's patients, reducing medication and enhancing quality of life.
fromNature
3 months ago
Alternative medicine

Daily briefing: The biggest single piece of meat ever grown in the lab

Alternative medicine
fromNature
3 months ago

'Big leap' for Parkinson's treatment: symptoms improve in stem-cells trials

Early-stage stem cell trials show promise for treating Parkinson's disease by replacing lost dopamine-producing neurons.
Wearables
fromwww.scientificamerican.com
4 months ago

New Form of Parkinson's Treatment Uses Real-Time Deep-Brain Stimulation

Deep-brain stimulation technology has dramatically improved symptoms for Parkinson's patients, reducing medication and enhancing quality of life.
fromMedium
3 weeks ago

How AI Is Enabling Clinical Trial Diversity

AI in clinical trials can improve participant diversity, ensuring more representative data for treatment effectiveness across different populations.
Science
fromNature
2 weeks ago

Found: a human gut microbe that makes cancer therapy more effective in mice

A gut bacterium can enhance cancer drug effectiveness by stimulating immune cells in mice, with plans for human trials.
fromSilicon Canals
3 weeks ago

Barcelona's Biorce raises 5M: CEO Pedro Coelho on tackling clinical trial delays with AI, US expansion, and hiring plans - Silicon Canals

Biorce is exactly the kind of pioneering company we're here to back. They're combining deep sector expertise with cutting-edge AI to solve what truly matters.
Healthcare
#ai-in-healthcare
Artificial intelligence
fromHackernoon
3 months ago

How AI Agents Could Have Supercharged Pfizer's COVID-19 Vaccine Development | HackerNoon

AI agents could accelerate vaccine development and drug discovery processes significantly.
Through active collaboration and learning, AI agents transform traditional procedures in healthcare research.
Artificial intelligence
fromHackernoon
3 months ago

How AI Agents Could Have Supercharged Pfizer's COVID-19 Vaccine Development | HackerNoon

AI agents could accelerate vaccine development and drug discovery processes significantly.
Through active collaboration and learning, AI agents transform traditional procedures in healthcare research.
fromMiami Herald
3 weeks ago

A paralyzed patient at UM just got Elon Musk's brain chip. Here are 5 takeaways

The Neuralink chip, known as the Link or Telepathy, was implanted by surgeons at the University of Miami Miller School of Medicine, marking the first such procedure at a Miami hospital. The chip allows RJ to wirelessly control a computer, as demonstrated by his ability to play video games using only his mind.
Artificial intelligence
#immunotherapy
Cancer
fromArs Technica
2 months ago

A new era in cancer therapies is at hand

New cancer therapies are advancing beyond traditional immunotherapy, providing safer, more effective treatment options for various tumor types.
Cancer
fromArs Technica
2 months ago

A new era in cancer therapies is at hand

New cancer therapies are advancing beyond traditional immunotherapy, providing safer, more effective treatment options for various tumor types.
fromFortune
3 weeks ago

Google DeepMind has grand ambitions to 'cure all diseases' with AI. Now, it's gearing up for its first human trials

Isomorphic Labs is set to launch human trials of AI-designed drugs, leveraging advancements from DeepMind's AlphaFold for drug discovery.
fromwww.theguardian.com
4 weeks ago

Is exercise really better than drugs for cancer remission? It's an appealing idea but it's misleading | Devi Sridhar

The study highlighted that combining structured exercise with chemotherapy can improve overall health outcomes in colon cancer recovery, showing that exercise should complement medical treatments.
Health
fromNature
1 month ago

Harvard vs Trump: what this epic battle means for science

Government actions jeopardize university research funding and threaten scientific progress at Harvard.
fromwww.bbc.com
1 month ago

Low aspirin dose 'cuts cancer risk in some people'

Prof Sir John Burn from Newcastle University stated that a study involving 1,879 individuals with Lynch syndrome shows a low dose of 75mg aspirin effectively reduces cancer risk as larger doses.
Cancer
fromNature
1 month ago

Obesity drugs show promise treating a new ailment: migraine

In a small study, the drug liraglutide reduced monthly migraine episodes by nearly half among people with obesity who experience the headache-inducing condition.
Alternative medicine
#diabetes
#cancer-treatment
Cancer
fromwww.theguardian.com
2 months ago

Immunotherapy trial helps cancer patients with tumours live 40% longer

Car T-cell therapy significantly prolongs survival in cancer patients by approximately 40% compared to standard treatments.
#weight-loss
Wearables
fromwww.theguardian.com
3 months ago

New daily weight-loss pill shows success at clinical trial

Orforglipron is a promising daily weight-loss pill that effectively aids in weight loss and reduces blood sugar in individuals with type 2 diabetes.
Wearables
fromwww.theguardian.com
3 months ago

New daily weight-loss pill shows success at clinical trial

Orforglipron is a promising daily weight-loss pill that effectively aids in weight loss and reduces blood sugar in individuals with type 2 diabetes.
fromwww.theguardian.com
1 month ago

Ministers plan to use NHS app to expand clinical trials as part of UK-wide drive

The NHS app will become the digital front door to the NHS, enabling citizens to participate in developing future medicines. Why not do it again to cure cancer and dementia?
UK news
Cancer
fromwww.theguardian.com
1 month ago

UK-wide drug trial hailed as a milestone' in leukaemia treatment

A UK trial found a chemotherapy-free treatment for leukaemia that improves outcomes for patients, suggesting a significant shift in treatment approaches.
fromLondon Business News | Londonlovesbusiness.com
1 month ago

Professor Akhil Tripathi on why he's proud his company ExciteOSA is sending people to sleep - London Business News | Londonlovesbusiness.com

ExciteOSA aims to improve sleep for those with sleep apnoea and reduce snoring, addressing significant health issues.
fromBoston.com
1 month ago

Boston drug company laying off 125 employees in R.I.

Business Vertex says the layoffs are due to the discontinuation of a Type 1 diabetes study.
NYC startup
#biotech
fromSilicon Canals
1 month ago
Startup companies

Mosanna Therapeutics raises 70.1M to disrupt sleep apnea treatment with nasal spray - Silicon Canals

fromSilicon Canals
1 month ago
Startup companies

Mosanna Therapeutics raises 70.1M to disrupt sleep apnea treatment with nasal spray - Silicon Canals

fromNature
1 month ago

Daily briefing: NIH foreign-grant cuts could leave thousands without care worldwide

Cuts to US foreign funding will abruptly halt hundreds of crucial clinical trials overseas, jeopardizing medical advancements and compromising global health initiatives.
Science
#cancer-research
Cancer
fromNature
1 month ago

Cancer fighting CAR-T cells show promising results for hard-to-treat tumours

CAR-T-cell therapy shows promise for treating solid tumors, potentially revolutionizing cancer treatment beyond blood cancers.
Cancer
fromwww.theguardian.com
2 months ago

Exercise better than drugs' after cancer treatment, international trial finds

Exercise can significantly reduce the risk of cancer recurrence and mortality, outperforming many standard drugs post-treatment.
Cancer
fromwww.nytimes.com
3 months ago

Immunotherapy Drug Spares Cancer Patients From Grisly Surgeries and Harsh Therapies

Dostarlimab immunotherapy shows promise for treating solid tumors with fewer severe side effects, achieving remarkable tumor regression in clinical trials.
Cancer
fromNature
3 months ago

Clinical trials by the numbers

Cancer is the second leading cause of death globally, requiring urgent advancements in diagnosis and treatment to keep pace with the rising incidence.
Emerging biopharmaceutical companies are increasingly dominating the oncology clinical trial landscape, reflecting their growing importance in cancer research.
Cancer
fromNature
1 month ago

Cancer fighting CAR-T cells show promising results for hard-to-treat tumours

CAR-T-cell therapy shows promise for treating solid tumors, potentially revolutionizing cancer treatment beyond blood cancers.
Cancer
fromwww.theguardian.com
2 months ago

Exercise better than drugs' after cancer treatment, international trial finds

Exercise can significantly reduce the risk of cancer recurrence and mortality, outperforming many standard drugs post-treatment.
Cancer
fromwww.nytimes.com
3 months ago

Immunotherapy Drug Spares Cancer Patients From Grisly Surgeries and Harsh Therapies

Dostarlimab immunotherapy shows promise for treating solid tumors with fewer severe side effects, achieving remarkable tumor regression in clinical trials.
Cancer
fromNature
3 months ago

Clinical trials by the numbers

Cancer is the second leading cause of death globally, requiring urgent advancements in diagnosis and treatment to keep pace with the rising incidence.
Emerging biopharmaceutical companies are increasingly dominating the oncology clinical trial landscape, reflecting their growing importance in cancer research.
#vaccines
fromNature
2 months ago

NIH grant cuts will axe clinical trials abroad - and could leave thousands without care

The NIH's new policy banning foreign subawards threatens ongoing international clinical trials, causing uncertainty for researchers and participants.
fromNews Center
2 months ago

New Scoring System Improves Colorectal Cancer Risk Prediction - News Center

The ARCAD database is a wonderful example of collaborative efforts around the world to create large patient-derived datasets that enable expanded research opportunities beyond the initial question addressed in the original design of a clinical trial.
Cancer
Cancer
fromenglish.elpais.com
2 months ago

Experimental drug fights lung cancer in nonsmokers: I feel like I did when I was healthy'

Lung cancer is increasingly diagnosed in non-smokers, particularly women, presenting new medical challenges.
Medicine
fromNature
2 months ago

Brain drugs can now cross the once impenetrable blood-brain barrier

Gordon's sons have new hope due to innovative treatments for Hunter syndrome, unlike her brothers who faced dire outcomes.
#pediatric-healthcare
Public health
fromCbsnews
2 months ago

Who can get updated COVID vaccines this fall? FDA will OK for high-risk groups, calls for new clinical trials

FDA is raising standards for COVID-19 booster approvals, focusing on high-risk groups.
Future vaccine updates for low-risk individuals will require robust clinical trials.
Parenting
fromArs Technica
2 months ago

The remarkable timeline of a custom gene-editing therapy to save a newborn

KJ received groundbreaking gene-editing therapy at just six months old, showcasing rapid advancements in clinical trial processes.
fromSilicon Canals
2 months ago

Dutch-based Hy2Care raises 4.5M from EIC, others for US clinical trial and commecial expansion - Silicon Canals

This funding round gives us the momentum needed to take the next big step in our journey, launching U.S. clinical trials and supporting our European commercialization strategy.
European startups
Data science
fromHackernoon
2 months ago

Efficient Bayesian Power Prior Survival Modeling with BayesPPDSurv | HackerNoon

The BayesPPDSurv package enhances clinical trial design by integrating historical data for more efficient time-to-event analysis.
#bayesian-statistics
Women
fromPsychology Today
2 months ago

Women With Alcohol Use Disorder Have A Different Disease

Alcohol use disorder (AUD) in women necessitates sex-specific treatment strategies due to distinct neurobiological and psychological differences from men.
Wearables
fromwww.mercurynews.com
2 months ago

Zepbound trims more belly fat than Wegovy, study shows

Eli Lilly's Zepbound outperformed Novo Nordisk's Wegovy in a recent study, showing superior weight loss and waist circumference reduction.
Alternative medicine
fromtime.com
2 months ago

Which Weight-Loss Drug Works the Best?

Zepbound shows superior weight loss compared to Wegovy in a recent clinical trial, influencing treatment decisions for obesity management.
Women in technology
fromwww.theguardian.com
2 months ago

Male bias in medical trials risks women's lives. But at least the data gap is finally being addressed | Caroline Criado Perez

The MHRA has recognized a significant gender imbalance in clinical trials, highlighting a critical issue in women's health research.
fromwww.theguardian.com
2 months ago

The Guardian view on bias in medical research: disregard for women's health belongs in the past | Editorial

Six years after Caroline Criado Perez's bestselling book 'Invisible Women,' women continue to be underrepresented in clinical trials, with significant disparities in research focus.
Women
fromwww.theguardian.com
2 months ago

Concerning' lack of female-only medical trials in UK, say health experts

Health experts are raising alarms about the significant under-representation of women in UK clinical trials, emphasizing the urgent need for more focused studies on women's health.
Women in technology
fromPsychology Today
2 months ago

Historical Abuses and Community-Based Participatory Research

The past research abuses at the Addiction Research Center (ARC) are emblematic of a broader, systemic issue of medical racism in U.S. healthcare.
Online Community Development
fromSFGATE
2 months ago

Bay Area biotech company slashes staff after losing $655 million in value

Pliant Therapeutics announced a 45% workforce reduction, equivalent to about 75 employees, to extend its cash runway after halting a critical Phase 2b trial over safety concerns.
Startup companies
fromwww.nytimes.com
3 months ago

Wegovy Can Treat a Dangerous Liver Disease, Study Finds

After 72 weeks, nearly 63 percent of those who received semaglutide injections and around 34 percent of those on placebo shots saw their liver condition improve.
Medicine
OMG science
fromNature
3 months ago

The dismantling of US science: can it survive Trump 2.0?

Trump's policies may irreversibly reshape US science funding and research, sparking fears for the future of scientific advancement.
fromSilicon Canals
3 months ago

Ghent-based Azalea Vision raises 9M to advance eye care with real-time adaptive smart lenses - Silicon Canals

Azalea Vision's first closing of its €15M Series A funding round enables the clinical trials of its revolutionary eye care technology, aimed at FDA approval.
European startups
fromHarvard Gazette
3 months ago

How halt in funding hurts efforts to ensure safety of patients in medical research - Harvard Gazette

The freeze of federal research grants to Harvard disrupts critical oversight of medical studies, impacting the rights and safety of research participants.
Privacy professionals
Mental health
fromHarvard Gazette
3 months ago

FDA-approved smoking cessation pill helps break vaping habit - Harvard Gazette

Varenicline significantly increases smoking cessation success among teens and young adults compared to behavioral counseling alone.
fromNature
3 months ago

A front-line antiviral drug disappoints against worrisome monkeypox strain

Tecovirimat, approved in Europe for mpox, showed limited effectiveness in hastening recovery in human clinical trials.
#brexit
UK news
fromwww.theguardian.com
3 months ago

Children with cancer cannot wait': the human cost of clinical trial delays after Brexit

Brexit is complicating cancer trials in the UK, raising costs and causing delays, preventing patients from accessing new treatments.
The eSMART trial faces significant logistical challenges post-Brexit.
Wearables
fromwww.nytimes.com
3 months ago

What to Know About Eli Lilly's Daily Pill for Weight Loss

Eli Lilly's orforglipron offers a potential oral treatment for obesity and diabetes, expanding access beyond current injected options.
fromNature
3 months ago

Japan's big bet on stem-cell therapies might soon pay off with breakthrough therapies

"After nearly two decades of hard work and setbacks, many say that Japan is on the cusp of bringing these therapies to market."
Alternative medicine
fromSilicon Valley Journals
3 months ago

A biotech company which developing therapies for orphan diseases raises $115M in funding

Glycomine's progress towards delivering the first disease-modifying therapy for a rare genetic disorder was bolstered by a $115 million Series C funding round.
Startup companies
#heart-failure
fromwww.theguardian.com
3 months ago
London startup

British hospitals introduce treatment for heart failure that cuts deaths by 62%

New treatment approach for heart failure patients dramatically reduces mortality and hospital readmissions.
fromtime.com
3 months ago

Pfizer Ends Development of Its Obesity Pill

Pfizer's decision to halt danuglipron development underscores the risks and complexities involved in creating new obesity treatments, particularly after significant financial investment and testing phases.
Wearables
fromwww.bbc.com
3 months ago

Skin cancer patients could join vaccine project

Thankfully I was still quite fit and since I've been on it, my tumours have all shrunk. Every time I go for a scan they seem to be shrinking, which is very exciting.
Cancer
fromwww.independent.co.uk
3 months ago

Starmer pledges to slash time needed to set up clinical trials to 150 days

‘Now, Britain used to be so much better than this, but we’ve taken our foot off the pedal,’ said a government spokesman, emphasizing the urgent need for improvement in the clinical trial setup process.
London startup
#cancer-immunotherapy
fromCancer
4 months ago
Cancer

TIL therapy for metastatic gastrointestinal cancers

A new TIL therapy shows promise for treating metastatic gastrointestinal cancers and may extend to other solid tumors.
Cancer
fromCancer
4 months ago

TIL therapy for metastatic gastrointestinal cancers

A new TIL therapy shows promise for treating metastatic gastrointestinal cancers and may extend to other solid tumors.
fromTechCrunch
4 months ago

Alphabet's AI drug discovery platform Isomorphic Labs raises $600M from Thrive | TechCrunch

Isomorphic Labs has raised $600 million to enhance its AI drug discovery efforts and support clinical trials.
OMG science
fromFuturism
4 months ago

Paralyzed Man Standing, Learning to Walk Again After Injection of Hacked Stem Cells

Stem cell treatment allows a paralyzed man to stand again after spinal cord injury.
Artificial intelligence
fromInfoQ
4 months ago

Google DeepMind Launches TxGemma: Advancing AI-Driven Drug Discovery and Development

TxGemma, an AI model from Google DeepMind, aims to accelerate drug discovery and clinical trials by improving prediction efficiency.
fromInsideHook
4 months ago

Lower Back Pain Drug Shows Promising Results

PP353 is a promising non-opioid treatment for chronic lower back pain, showing significant improvement in clinical trials.
fromWIRED
4 months ago

Sperm Stem Cells Were Used for the First Time in an Attempt to Restore Fertility

The initial transplant demonstrated safety, with normal hormone levels and no harm to testicular tissue, though sperm is still absent.
Digital life
fromWIRED
4 months ago

Synchron's Brain-Computer Interface Now Has Nvidia's AI

Synchron's tech allows non-invasive brain-computer interface development, enabling data collection for AI models using avatars as time stamps.
Social justice
fromCornell Chronicle
4 months ago

More diverse investigators could help diversify clinical trials | Cornell Chronicle

Black Americans trust Black doctors more in medical studies, leading to better enrollment in clinical trials.
US news
fromwww.nytimes.com
4 months ago

Chaos at the V.A.: Inside the DOGE Cuts Disrupting the Veterans Agency

Budget cuts at the V.A. have disrupted critical cancer drug trials for veterans, halting essential research due to hiring freezes.
fromArs Technica
4 months ago

Saliva that fights norovirus? Experimental oral vaccine is nothing to spit at.

In this Phase I study for an experimental norovirus vaccine, we found it safely stimulated immune responses in older adults, crucial for combating severe infections.
Coronavirus
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