#drug-development

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#neuroscience
OMG science
fromwww.bostonherald.com
5 months ago

A yoga pill' to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stress

A new study reveals a brain pathway that can help combat anxiety by regulating voluntary breathing, offering potential for future calming drugs.
Science
fromFast Company
9 months ago

How neuroscientists are designing a safer opioid

Researchers are working on creating a new drug that mimics the pain-relief effects of opioids without their addictive and deadly effects.
OMG science
fromwww.bostonherald.com
5 months ago

A yoga pill' to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stress

A new study reveals a brain pathway that can help combat anxiety by regulating voluntary breathing, offering potential for future calming drugs.
Science
fromFast Company
9 months ago

How neuroscientists are designing a safer opioid

Researchers are working on creating a new drug that mimics the pain-relief effects of opioids without their addictive and deadly effects.
more#neuroscience
#cancer-research
fromZDNET
8 months ago
Artificial intelligence

Absci and Memorial Sloan Kettering partner to search for cancer drugs using AI

Artificial intelligence in drug development shows promise through collaborations like MSK and Absci's innovative partnership.
fromFast Company
1 day ago
Cancer

How federal funding cuts could threaten America's lead in cancer research

U.S. cancer research relies on a complex, interdependent ecosystem vulnerable to disruptions that threaten progress and new treatments.
fromNature
1 week ago
Cancer

Four rising stars at the forefront of cancer research

Young researchers are innovating in cancer drug development, focusing on pioneering techniques like cancer reversion to reduce the need for traditional treatments.
Artificial intelligence
fromZDNET
8 months ago

Absci and Memorial Sloan Kettering partner to search for cancer drugs using AI

Artificial intelligence in drug development shows promise through collaborations like MSK and Absci's innovative partnership.
Cancer
fromFast Company
1 day ago

How federal funding cuts could threaten America's lead in cancer research

U.S. cancer research relies on a complex, interdependent ecosystem vulnerable to disruptions that threaten progress and new treatments.
Cancer
fromNature
1 week ago

Four rising stars at the forefront of cancer research

Young researchers are innovating in cancer drug development, focusing on pioneering techniques like cancer reversion to reduce the need for traditional treatments.
more#cancer-research
#alzheimers
fromwww.orlandosentinel.com
1 month ago
OMG science

Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove it

An experimental treatment shows promise in delaying Alzheimer's symptoms in at-risk individuals, raising concerns about funding halting patient access.
fromNews Center
1 week ago
Alternative medicine

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study - News Center

NU-9 shows promise in improving neuron health across neurodegenerative diseases like ALS and Alzheimer's by targeting their common mechanisms.
fromwww.orlandosentinel.com
1 month ago
OMG science

Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove it

An experimental treatment shows promise in delaying Alzheimer's symptoms in at-risk individuals, raising concerns about funding halting patient access.
fromNews Center
1 week ago
Alternative medicine

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study - News Center

NU-9 shows promise in improving neuron health across neurodegenerative diseases like ALS and Alzheimer's by targeting their common mechanisms.
more#alzheimers
#weight-loss
Medicine
fromWIRED
9 months ago

A New Wave of Anti-Obesity Drugs Is on the Way

Tirzepatide's dual receptor activation may contribute to its efficacy in weight loss, while GIP's role is not fully understood yet.
Alternative medicine
fromWIRED
2 weeks ago

An Experimental Obesity Pill Mimics Gastric Bypass Surgery

The drug developed at MIT shows promise as a weight loss treatment by enhancing nutrient absorption and regulating hunger hormones.
Medicine
fromWIRED
9 months ago

A New Wave of Anti-Obesity Drugs Is on the Way

Tirzepatide's dual receptor activation may contribute to its efficacy in weight loss, while GIP's role is not fully understood yet.
Alternative medicine
fromWIRED
2 weeks ago

An Experimental Obesity Pill Mimics Gastric Bypass Surgery

The drug developed at MIT shows promise as a weight loss treatment by enhancing nutrient absorption and regulating hunger hormones.
more#weight-loss
#clinical-trials
Tech industry
fromHackernoon
2 months ago

Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoon

Quantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
Artificial intelligence
fromTNW | Future-Of-Work
2 months ago

Will AI revolutionise drug development? Researchers say it depends on how it's used

AI in drug development shows promise but requires cautious optimism and realistic expectations.
Despite excitement, AI has not yet significantly improved drug success rates in clinical trials.
Wearables
fromtime.com
2 weeks ago

Pfizer Ends Development of Its Obesity Pill

Pfizer has halted the development of danuglipron due to safety concerns, but remains committed to exploring other obesity treatment options.
OMG science
fromwww.theguardian.com
6 months ago

Which disease-modifying Alzheimer's drugs are the most promising?

The UK health watchdog has rejected two new Alzheimer's drugs due to concerns over their effectiveness and potential side effects.
fromwww.nytimes.com
5 months ago
Medicine

Trial of Controversial Alzheimer's Drug Halted After Disappointing Results

Cassava Sciences halted the advanced trial for simufilam as it failed to reduce cognitive decline in Alzheimer's patients, disappointing many.
fromSFGATE
3 months ago
Medicine

Bay Area biotech firm once worth $13B lays off all but 15 workers

Allakos announces failure of pivotal clinical trial for chronic hives drug AK006, resulting in a 75% staff layoff.
Tech industry
fromHackernoon
2 months ago

Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoon

Quantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
Artificial intelligence
fromTNW | Future-Of-Work
2 months ago

Will AI revolutionise drug development? Researchers say it depends on how it's used

AI in drug development shows promise but requires cautious optimism and realistic expectations.
Despite excitement, AI has not yet significantly improved drug success rates in clinical trials.
Wearables
fromtime.com
2 weeks ago

Pfizer Ends Development of Its Obesity Pill

Pfizer has halted the development of danuglipron due to safety concerns, but remains committed to exploring other obesity treatment options.
OMG science
fromwww.theguardian.com
6 months ago

Which disease-modifying Alzheimer's drugs are the most promising?

The UK health watchdog has rejected two new Alzheimer's drugs due to concerns over their effectiveness and potential side effects.
fromwww.nytimes.com
5 months ago
Medicine

Trial of Controversial Alzheimer's Drug Halted After Disappointing Results

Cassava Sciences halted the advanced trial for simufilam as it failed to reduce cognitive decline in Alzheimer's patients, disappointing many.
fromSFGATE
3 months ago
Medicine

Bay Area biotech firm once worth $13B lays off all but 15 workers

Allakos announces failure of pivotal clinical trial for chronic hives drug AK006, resulting in a 75% staff layoff.
more#clinical-trials
OMG science
fromenglish.elpais.com
3 weeks ago

John Hartwig, chemist: The situation for science in the United States is terrible, these are the steps of authoritarian regimes to take power'

John Hartwig's work in catalysis significantly impacts drug production and the economy, yet it often goes unnoticed compared to more famous scientific pursuits.
#healthcare-innovation
fromwww.theguardian.com
1 month ago
Mental health

New drug for lower back pain could be a gamechanger'

A new antibiotic drug, PP353, shows promise in treating severe back pain caused by infections, potentially changing treatment paradigms.
fromwww.theguardian.com
1 month ago
Mental health

New drug for lower back pain could be a gamechanger'

A new antibiotic drug, PP353, shows promise in treating severe back pain caused by infections, potentially changing treatment paradigms.
more#healthcare-innovation
#biotech
fromSFGATE
1 month ago
NYC startup

Bay Area biotech company, once worth $1.2 billion, lays off almost entire staff

Cargo Therapeutics is laying off nearly all its employees after ceasing drug development due to trial failures, marking a major decline for the biotech firm.
fromTechCrunch
5 months ago
Miscellaneous

Archon emerges from stealth with $20M and 'antibody cages' to power up drug development | TechCrunch

Archon Biosciences aims to revolutionize antibody treatments through innovative protein 'cages' that improve drug binding and efficacy.
fromSFGATE
1 month ago
NYC startup

Bay Area biotech company, once worth $1.2 billion, lays off almost entire staff

Cargo Therapeutics is laying off nearly all its employees after ceasing drug development due to trial failures, marking a major decline for the biotech firm.
fromTechCrunch
5 months ago
Miscellaneous

Archon emerges from stealth with $20M and 'antibody cages' to power up drug development | TechCrunch

Archon Biosciences aims to revolutionize antibody treatments through innovative protein 'cages' that improve drug binding and efficacy.
more#biotech
#artificial-intelligence
Startup companies
fromFast Company
1 month ago

These 10 biotech companies are changing how we discover new drugs and treat complex diseases

Biotech companies are harnessing AI and cutting-edge research tools to enhance drug development and diagnostics.
Startup companies
fromFast Company
1 month ago

These 10 biotech companies are changing how we discover new drugs and treat complex diseases

Biotech companies are harnessing AI and cutting-edge research tools to enhance drug development and diagnostics.
more#artificial-intelligence
#medical-research
Fundraising
fromwww.theguardian.com
1 month ago

Many life-saving drugs fail for lack of funding. But there's a solution: desperate rich people

La Fondation Brocher is key in medical ethics research, influencing drug development, yet many effective drugs remain abandoned.
fromNature
7 months ago
Medicine

2021: Anti-amyloid antibodies take a bumpy road to the clinic

The initial disease-modifying therapy for Alzheimer's sparked complex reactions rather than unbridled joy.
Fundraising
fromwww.theguardian.com
1 month ago

Many life-saving drugs fail for lack of funding. But there's a solution: desperate rich people

La Fondation Brocher is key in medical ethics research, influencing drug development, yet many effective drugs remain abandoned.
fromNature
7 months ago
Medicine

2021: Anti-amyloid antibodies take a bumpy road to the clinic

The initial disease-modifying therapy for Alzheimer's sparked complex reactions rather than unbridled joy.
more#medical-research
#pain-management
fromNature
7 months ago
Alternative medicine

Pain researchers must learn from the opioid crisis

A new strategy for analgesic drug development is necessary to prevent opioid addiction and find safer pain relief alternatives.
fromCbsnews
2 months ago
Alternative medicine

FDA OK's painkiller designed to end opioids' addiction and overdose risk

Journavx offers a new pain management solution without the addiction risks of opioids.
fromNature
7 months ago
Alternative medicine

Pain researchers must learn from the opioid crisis

A new strategy for analgesic drug development is necessary to prevent opioid addiction and find safer pain relief alternatives.
fromCbsnews
2 months ago
Alternative medicine

FDA OK's painkiller designed to end opioids' addiction and overdose risk

Journavx offers a new pain management solution without the addiction risks of opioids.
more#pain-management
#antimicrobial-resistance
fromwww.scientificamerican.com
5 months ago
Science

The U.S. Must Lead the Global Fight against Superbugs

Antimicrobial resistance could lead to 39 million deaths by 2050; urgent U.S. government action is essential to combat this crisis.
fromsiliconvalleyjournals.com
3 months ago
Medicine

Glox Therapeutics Awarded Share of 3M Collaborative Discovery Programme Funding from Cystic Fibrosis Antimicrobial Resistance Syndicate

Glox Therapeutics is developing precision antibiotics to address antimicrobial resistance in cystic fibrosis.
fromwww.scientificamerican.com
5 months ago
Science

The U.S. Must Lead the Global Fight against Superbugs

Antimicrobial resistance could lead to 39 million deaths by 2050; urgent U.S. government action is essential to combat this crisis.
fromsiliconvalleyjournals.com
3 months ago
Medicine

Glox Therapeutics Awarded Share of 3M Collaborative Discovery Programme Funding from Cystic Fibrosis Antimicrobial Resistance Syndicate

Glox Therapeutics is developing precision antibiotics to address antimicrobial resistance in cystic fibrosis.
more#antimicrobial-resistance
#global-health
OMG science
fromwww.theguardian.com
3 months ago

Breakthrough drugs herald new era' in battle against dementia, experts predict

Pills preventing or mitigating Alzheimer's disease are emerging, with new drugs set to be available, promising a new era in dementia care.
fromwww.dw.com
3 months ago
Medicine

Novel antibiotics: Regional research is (half) the solution DW 01/15/2025

Antibiotic resistance is escalating, necessitating urgent local drug development, particularly in low- and middle-income countries.
OMG science
fromwww.theguardian.com
3 months ago

Breakthrough drugs herald new era' in battle against dementia, experts predict

Pills preventing or mitigating Alzheimer's disease are emerging, with new drugs set to be available, promising a new era in dementia care.
fromwww.dw.com
3 months ago
Medicine

Novel antibiotics: Regional research is (half) the solution DW 01/15/2025

Antibiotic resistance is escalating, necessitating urgent local drug development, particularly in low- and middle-income countries.
more#global-health
OMG science
fromWashington Post
3 months ago

Martin Karplus, who took biochemistry to cyberspace, dies at 94

Martin Karplus revolutionized theoretical chemistry by merging physics and computer modeling, which advanced our understanding of biochemical reactions.
Medicine
fromNews Center
4 months ago

Esteemed Molecular Biologist Named Winner of 2025 Kimberly Prize - News Center

Ron Evans, PhD, received the Kimberly Prize for his breakthroughs in nuclear hormone receptors, impacting drug development and improving human health.
fromSilicon Canals
5 months ago
Miscellaneous

Eindhoven's Chromodynamics secures 2M funding - Silicon Canals

Chromodynamics raised €2M to advance its microscopy technology, aiming to revolutionize biomedical research and speed up drug development processes.
#mental-health
fromNature
5 months ago
OMG science

New schizophrenia drug could treat Alzheimer's disease

A new era in psychiatric medicine is suggested by the approval of innovative drugs, though not all trials yield positive results.
fromtime.com
6 months ago
Medicine

Safer Psychedelic Drugs May Be Coming

Psychedelics offer therapeutic potential for mental health, yet face challenges including safety concerns and regulatory hurdles that could be addressed through next-generation approaches.
fromFuturism
6 months ago
Medicine

Startups Are Biohacking Psychedelic Drugs to Make Sure You Never Have a Bad Trip Again

Pharmaceutical companies are developing next-generation psychedelics to serve as safer psychotherapy treatments, with promising early research on compounds like R-MDMA.
OMG science
fromNature
5 months ago

New schizophrenia drug could treat Alzheimer's disease

A new era in psychiatric medicine is suggested by the approval of innovative drugs, though not all trials yield positive results.
fromtime.com
6 months ago
Medicine

Safer Psychedelic Drugs May Be Coming

Psychedelics offer therapeutic potential for mental health, yet face challenges including safety concerns and regulatory hurdles that could be addressed through next-generation approaches.
fromFuturism
6 months ago
Medicine

Startups Are Biohacking Psychedelic Drugs to Make Sure You Never Have a Bad Trip Again

Pharmaceutical companies are developing next-generation psychedelics to serve as safer psychotherapy treatments, with promising early research on compounds like R-MDMA.
more#mental-health
#health-policy
Miscellaneous
fromIndependent
5 months ago

Explainer: What we know about the new 'gamechanger' anti-smoking pill and when will it arrive in Ireland?

Varenicline is an anti-smoking pill introduced in the UK health service as a new solution for smoking cessation.
fromAxios
5 months ago
Miscellaneous

RFK Jr. vs. Vivek: Trump world's two paths for pharma regulation

Ramaswamy and Kennedy's differing views on drug regulation add uncertainty for pharmaceutical companies under the new administration.
Miscellaneous
fromIndependent
5 months ago

Explainer: What we know about the new 'gamechanger' anti-smoking pill and when will it arrive in Ireland?

Varenicline is an anti-smoking pill introduced in the UK health service as a new solution for smoking cessation.
fromAxios
5 months ago
Miscellaneous

RFK Jr. vs. Vivek: Trump world's two paths for pharma regulation

Ramaswamy and Kennedy's differing views on drug regulation add uncertainty for pharmaceutical companies under the new administration.
more#health-policy
fromNature
5 months ago
Medicine

Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation - Nature

AKT1 E17K mutation poses a challenge for treatment; targeted inhibitors offer a promising solution without the side effect of hyperglycaemia.
#chemistry
OMG science
fromNature
5 months ago

Chemists make 'impossible' molecules that break 100-year-old bonding rule

Chemists successfully synthesized anti-Bredt olefins, previously thought too unstable, paving the way for novel drug candidate synthesis.
fromNature
5 months ago
Miscellaneous

Daily briefing: 'Impossible' molecules break 100-year old chemical rule

Chemists have synthesized a molecule that challenges the long-standing Bredt's rule, opening new avenues in drug development.
OMG science
fromNature
5 months ago

Chemists make 'impossible' molecules that break 100-year-old bonding rule

Chemists successfully synthesized anti-Bredt olefins, previously thought too unstable, paving the way for novel drug candidate synthesis.
fromNature
5 months ago
Miscellaneous

Daily briefing: 'Impossible' molecules break 100-year old chemical rule

Chemists have synthesized a molecule that challenges the long-standing Bredt's rule, opening new avenues in drug development.
more#chemistry
fromwww.theguardian.com
5 months ago
Exercise

Exercise in a pill: have scientists really found a drug that's as good for you as a 10km run?

Mimetics like LaKe may replicate some benefits of exercise, but their true usefulness and safety remain uncertain.
#medical-innovation
OMG science
fromLos Angeles Times
5 months ago

Berkeley startup wins government award to develop radiation and lead poisoning treatment

HOPO Therapeutics aims to develop drugs that selectively target and remove toxic metals from the body, posing a significant health threat.
Artificial intelligence
fromFast Company
6 months ago

How to transform scientific discoveries into better treatments

Transforming scientific discoveries into effective treatments requires innovative collaboration across disciplines and sectors to address complex healthcare challenges.
fromwww.theguardian.com
6 months ago
Miscellaneous

Breakthrough by William Pao review the drugs do work

Creative innovation in drug development becomes a transformative force in medicine, driven by personal dedication and often serendipitous discoveries.
OMG science
fromLos Angeles Times
5 months ago

Berkeley startup wins government award to develop radiation and lead poisoning treatment

HOPO Therapeutics aims to develop drugs that selectively target and remove toxic metals from the body, posing a significant health threat.
Artificial intelligence
fromFast Company
6 months ago

How to transform scientific discoveries into better treatments

Transforming scientific discoveries into effective treatments requires innovative collaboration across disciplines and sectors to address complex healthcare challenges.
fromwww.theguardian.com
6 months ago
Miscellaneous

Breakthrough by William Pao review the drugs do work

Creative innovation in drug development becomes a transformative force in medicine, driven by personal dedication and often serendipitous discoveries.
more#medical-innovation
fromBusiness Insider
6 months ago
Miscellaneous

Activist hedge fund Starboard met with Pfizer last week. Here's what went down.

Starboard is advocating for increased accountability and improvements in Pfizer's operational and financial strategies. Smith highlights a poor return on investments.
fromData Matters Privacy Blog
6 months ago
European startups

Top Trends in the European Digital Health/AI Market | Data Matters Privacy Blog

Digital health technologies are rapidly transforming drug development and healthcare delivery, with strong growth despite regulatory challenges.
#eli-lilly
OMG science
fromtime.com
10 months ago

The Next Potential Alzheimer's Drug Clears a Big Hurdle

Drug companies are making progress in Alzheimer's treatment with FDA panel's positive evaluation of Eli Lilly's donanemab.
from24/7 Wall St.
6 months ago
Business

Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030

Eli Lilly's stock has risen dramatically over recent years, showcasing strong market confidence and growth potential.
Future projections for Eli Lilly's earnings and drug performance indicate significant growth opportunities despite recent safety concerns.
OMG science
fromtime.com
10 months ago

The Next Potential Alzheimer's Drug Clears a Big Hurdle

Drug companies are making progress in Alzheimer's treatment with FDA panel's positive evaluation of Eli Lilly's donanemab.
from24/7 Wall St.
6 months ago
Business

Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030

Eli Lilly's stock has risen dramatically over recent years, showcasing strong market confidence and growth potential.
Future projections for Eli Lilly's earnings and drug performance indicate significant growth opportunities despite recent safety concerns.
more#eli-lilly
Artificial intelligence
fromZDNET
7 months ago

How digital twins could save time, money, and lives in developing prescription drugs

Digital twins in healthcare can transform drug development by simulating patient health, predicting outcomes, and optimizing treatment strategies.
fromFast Company
11 months ago
Data science

DeepMind's new AlphaFold 3 expands to DNA, RNA modeling

AlphaFold 3 extends protein structure prediction to modeling interactions with DNA, RNA, and drugs, aiding in drug development.
OMG science
fromNews Center
10 months ago

Feinberg Scientists to Lead Grant Studying Autism, Schizophrenia - News Center

Northwestern Medicine secures $17 million grant to explore genetic causes of autism and schizophrenia for new drug development.
fromNature
10 months ago
Data science

A disease-associated gene desert directs macrophage inflammation through ETS2 - Nature

Only 10% of drugs developed for autoimmune diseases are successful due to a lack of efficacy and poor understanding of disease mechanisms.
Medicine
fromArs Technica
9 months ago

Alzheimer's scientist indicted for allegedly falsifying data in $16M scheme

An Alzheimer's researcher allegedly falsified data to secure $16 million in research funding for an Alzheimer's drug, raising doubts about the integrity of the research.
The investigation revealed long-standing and egregious misconduct in data management by the researcher, leading to questions about the authenticity of the work.
OMG science
fromNature
10 months ago

Ketamine for depression: slow-release pills could make treatment more accessible

Ketamine tablet could revolutionize depression treatment, offering a more convenient alternative to intravenous administration with reduced side effects.
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