The freezer is filled with blue-lidded tubes of cows' blood, ready to be defrosted and used to feed the colony of mosquitoes. Nombuso Princess Bhembe tends the mosquitoes at Eswatini's national insectary, part of the southern African country's push to eliminate malaria.
Kelly Chibale describes the drug discovery process as a fairy-tale quest, stating, 'It doesn't mean that there aren't surprises or miracles. They do happen, but you have to kiss many frogs before you meet the prince.' This metaphor illustrates the challenges and unpredictability in finding effective medicines.
From Africa to Latin America to Asia, babies have been carried in cloth wraps on their mothers' backs for centuries. Now, the practice of generations of women could become a lifesaving tool in the fight against malaria. Researchers in Uganda have found that treating wraps with the insect repellent permethrin cut rates of malaria in the infants carried in them by two-thirds.
Fever ravaged the body of 5-year-old Suza Kenyaba as she sweated and shivered on a thin mattress in a two-room clinic in the Democratic Republic of Congo. The pigtailed girl who liked pretty dresses was battling malaria and desperately needed medication that could save her life. That medication, already purchased by a U.S.-taxpayer-funded program, was tantalizingly close - a little more than seven miles away.
Understanding the interactions between RIFIN proteins and immune receptors is crucial for developing strategies to combat malaria, particularly in regions heavily affected by the disease.
Historically, blackwater fever was seen among European expatriates who took small doses of quinine as an antimalarial, and became less common when other drugs took over.
The mosquitoes released in Djibouti are a vital tool in combating malaria, but their effectiveness needs to be complemented by existing prevention methods like nets and vaccines.